課程時間：2019年S季
授課教授：KUANG Becki Yi & NI Rong
我覺得教授：很好！！！！
評分標準：attendance 10% + assignment 10% + quiz (choose best 3 out of 4) 15% + midterm 30% + final 35%
這門課的Grade：Not too bad
BIEN2610 Chemical Biology for Engineers
内容和LIFS生化差别还是蛮大的，主要讲是一些分子生物的工科应用之类的东西。
我觉得这个课应该改名叫Introduction to Molecular Bioengineering
由于这个课是随着Bioengineering的新major应运而生的新课，大家可能不是很了解，我就列一下syllabus吧
Week 1-3 Nucleic acid & nucleic acid engineering | ||
Feb. 1 (Fri) | Lecture 1 | Introduction of nucleic acid and gene |
Feb. 4 (Mon) | Lecture 2 | Basics of genetics and genomics |
Feb. 8 (Fri) | Lecture 3 | DNA mutation & damage repair |
Feb. 11 (Mon) | Lecture 4 | RNA processing & catalysis |
Feb. 15 (Fri) | Lecture 5 | Gene editing & DNA cloning |
Feb. 18 (Mon) | Lecture 6 | Engineering of artificial nucleic acid (Quiz) |
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Week 4-6 Protein & protein engineering (Rong Ni) | ||
Feb. 22 (Fri) | Lecture 7 | Introduction of amino acid & peptide |
Feb. 25 (Mon) | Lecture 8 | Basics of protein: the basic building block of life |
Mar. 1 (Fri) | Lecture 9 | Enzyme & structural protein |
Mar. 4 (Mon) | Lecture 10 | Antigen & antibody; bioactive small peptide |
Mar. 8 (Fri) | Lecture 11 | Designing proteins for biological purposes I |
Mar. 11 (Mon) | Lecture 12 | Designing proteins for biological purposes II (Quiz) |
Topics of written assignment will be releases on Canvas. | ||
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Week 7 Small biomolecules (Rong Ni) | ||
Mar. 15 (Fri) | Lecture 13 | Metabolites & their use in health care |
Mar. 18 (Mon) | Lecture 14 | Ligand: important drug targets |
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Week 8-12 The principle and application of bioengineering | ||
Mar. 22 (Fri) | Midterm | |
Mar. 25 (Mon) | Lecture 15 | Combinatorial chemistry and molecular evolution I |
Mar. 25 (Mon, Tutorial) | Lecture 16 | Combinatorial chemistry and molecular evolution II (content will not be include in final) |
Mar. 29 (Fri) | Lecture 17 | Labeling of biomolecules |
April 1 (Mon) | Lecture 18 | Tracking of biomolecules (Quiz) |
April 8 (Mon) | Lecture 19 | Monitoring interactions between biomolecules |
April 12 (Fri) | Lecture 20 | Sanger sequencing & microarray |
April 15 (Mon) | Lecture 21 | Chemical assisted sequencing for identifying base modification |
Upload written assignment onto Canvas. | ||
April 26 (Fri) | Lecture 22 | Chemical assisted sequencing for structural identification |
April 29 (Mon) | Lecture 23 | Protein separation and identification (Quiz) |
May 3 (Fri) | Lecture 24 | Mass spectrometry and proteomics (Henry Lam, guest lecture) |
May 6 (Mon) | Tutorial (Q&A) | Tutorial slides will be updated on Canvas during study break (May 10-16) |
讲的东西都是很introduction的level，很多东西和CENG4640重合（但是4640的Prof SUN Fei讲课讲不清楚，参考那几篇CENG1600的评价，但是SUN Fei之前的老板拿了诺奖啊）。
上课很容易听懂，1/4内容是高中学过的。Becki部分的ppt做的非常简洁而清晰，非常适合课后复习。Ni Rong的part就会放上好多东西，还有很多很confusing的case study，相对来说难理解一点。
Quiz、midterm和final都让带cheat sheet，可以把ppt所有内容全抄下来带去（虽然时间很紧张几乎没有时间看）。另外这些考试全部non-cumulative。
需要背的分子结构的部分并不是很多，所以workload并不大。每次workload集中的时候也就是quiz之前做cheat sheet了。
期中有一个小论文作业，3页A4，不难，那一天出来查查资料写一下就可以啦。
第一年的课，只有十几个人上，这种小班一般给龟就比较松啦。Overall 90分拿A（但是91就有A+……
另外说一下教授。Becki在分子生物工程（尤其是DNA、RNA方面）的学术研究很高，之前在美国和日本有过非常丰富的research经历，人也非常和善，非常棒的教授！对DNA、RNA等方面有兴趣的童鞋可以跟她做做research～
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