課程：BIEN2610
作者：hlica [12级 摸鱼]
創建於：2019-05-03 16:32:12
更新於：2019-06-01 20:50:35
課程時間：2019年S季
授課教授：KUANG Becki Yi & NI Rong
我覺得教授：很好！！！！
評分標準：attendance 10% + assignment 10% + quiz (choose best 3 out of 4) 15% + midterm 30% + final 35%
這門課的Grade：Not too bad
BIEN2610 Chemical Biology for Engineers
内容和LIFS生化差别还是蛮大的，主要讲是一些分子生物的工科应用之类的东西。
我觉得这个课应该改名叫Introduction to Molecular Bioengineering
由于这个课是随着Bioengineering的新major应运而生的新课，大家可能不是很了解，我就列一下syllabus吧
Week 1-3 Nucleic acid & nucleic acid engineering
Feb. 1 (Fri)
Lecture 1
Introduction of nucleic acid and gene
Feb. 4 (Mon)
Lecture 2
Basics of genetics and genomics
Feb. 8 (Fri)
Lecture 3
DNA mutation & damage repair
Feb. 11 (Mon)
Lecture 4
RNA processing & catalysis
Feb. 15 (Fri)
Lecture 5
Gene editing & DNA cloning
Feb. 18 (Mon)
Lecture 6
Engineering of artificial nucleic acid (Quiz)
Week 4-6 Protein & protein engineering (Rong Ni)
Feb. 22 (Fri)
Lecture 7
Introduction of amino acid & peptide
Feb. 25 (Mon)
Lecture 8
Basics of protein: the basic building block of life
Mar. 1 (Fri)
Lecture 9
Enzyme & structural protein
Mar. 4 (Mon)
Lecture 10
Antigen & antibody; bioactive small peptide
Mar. 8 (Fri)
Lecture 11
Designing proteins for biological purposes I
Mar. 11 (Mon)
Lecture 12
Designing proteins for biological purposes II (Quiz)
Topics of written assignment will be releases on Canvas.
Week 7 Small biomolecules (Rong Ni)
Mar. 15 (Fri)
Lecture 13
Metabolites & their use in health care
Mar. 18 (Mon)
Lecture 14
Ligand: important drug targets
Week 8-12 The principle and application of bioengineering
Mar. 22 (Fri)
Midterm
Mar. 25 (Mon)
Lecture 15
Combinatorial chemistry and molecular evolution I
Mar. 25 (Mon, Tutorial)
Lecture 16
Combinatorial chemistry and molecular evolution II
(content will not be include in final)
Mar. 29 (Fri)
Lecture 17
Labeling of biomolecules
April 1 (Mon)
Lecture 18
Tracking of biomolecules (Quiz)
April 8 (Mon)
Lecture 19
Monitoring interactions between biomolecules
April 12 (Fri)
Lecture 20
Sanger sequencing & microarray
April 15 (Mon)
Lecture 21
Chemical assisted sequencing for identifying base modification
Upload written assignment onto Canvas.
April 26 (Fri)
Lecture 22
Chemical assisted sequencing for structural identification
April 29 (Mon)
Lecture 23
Protein separation and identification (Quiz)
May 3 (Fri)
Lecture 24
Mass spectrometry and proteomics (Henry Lam, guest lecture)
May 6 (Mon)
Tutorial (Q&A)
Tutorial slides will be updated on Canvas during study break (May 10-16)
讲的东西都是很introduction的level，很多东西和CENG4640重合（但是4640的Prof SUN Fei讲课讲不清楚，参考那几篇CENG1600的评价，但是SUN Fei之前的老板拿了诺奖啊）。
上课很容易听懂，1/4内容是高中学过的。Becki部分的ppt做的非常简洁而清晰，非常适合课后复习。Ni Rong的part就会放上好多东西，还有很多很confusing的case study，相对来说难理解一点。
Quiz、midterm和final都让带cheat sheet，可以把ppt所有内容全抄下来带去（虽然时间很紧张几乎没有时间看）。另外这些考试全部non-cumulative。
需要背的分子结构的部分并不是很多，所以workload并不大。每次workload集中的时候也就是quiz之前做cheat sheet了。
期中有一个小论文作业，3页A4，不难，那一天出来查查资料写一下就可以啦。
第一年的课，只有十几个人上，这种小班一般给龟就比较松啦。Overall 90分拿A（但是91就有A+……
另外说一下教授。Becki在分子生物工程（尤其是DNA、RNA方面）的学术研究很高，之前在美国和日本有过非常丰富的research经历，人也非常和善，非常棒的教授！对DNA、RNA等方面有兴趣的童鞋可以跟她做做research～
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